According to WHO, every year, over two million deaths worldwide are caused by bacterial infections due to infected food products and drinks. The emergence of new bacterial mutations, their antibiotic resistance, and regular outbreaks require the development of a new generation of bacterial coatings. This is a burning issue today.
A team of researchers from the Department of Optics and Spectroscopy of the VSU Faculty of Physics, including Alexey Perepelitsa, an assistant at the Department of Optics and Spectroscopy of the Faculty of Physics, is developing an innovative technology used to generate biologically compatible antimicrobial protective coatings and polymer films to treat various surfaces. The study is a part of the project “Photobacterium coatings based on metallic sulphide nanoparticles and molecules of organic dyes used to disinfect surfaces”. Basically the researchers are planning to create a material based on metallic sulphide nanoparticles which could be used to disinfect various surfaces.
“The development of a new generation of bacterial and photobacterium (whose bacterial effect is activated under exposure to light) coatings is very timely. These materials could be used to sterilise walls in medical institutions and on industrial premises. We are planning to create a unique product by means of a developed technology of low toxicity used to generate solutions of colloidal nanoparticles of Ag2S, CdS, ZnxCd1-xS and their associates with molecules of organic dyes,” said Alexey Perepelitsa.
Today, disinfection is normally carried out by means of compositions based on chlorine-containing organic substances (alkyldimethylbenzylammonium chloride, chlorohexidine bigluconate, etc.) and silver nanoparticles. They are quite effective but can be harmful. Recently, these older substances have been added to coating compositions. According to the study of Autonomous Non-Commercial Organization “Rossiiskaya Systema Kachestva” (Russian quality system), their claimed antimicrobial effects do not match the facts and it is no more than marketing speak.
Voronezh scientists use a comprehensive approach: to develop a disinfectant, they will use molecules of organic dyes-singlet oxygen photosensitisers (triethylene blue, thionin, etc.) and their effect will be reinforced by conjugation with metallic sulphide nanoparticles with size dependable optical properties.
The developed coatings can be used to disinfect surfaces in medical and educational institutions and to treat the inner surfaces in ambulance cars. They are also suitable for mass production. VSU press-centre.